ენტეროპათოგენური E.coli-ს მიმართ მოქმედების ფართო სპექტრის ბაქტერიოფაგის გამოყოფა და სურსათის დეკონტამინაციური ეფექტის შესწავლა სამოდელო ცდებში

The incidence of diseases caused by enteropathogenic Escherichia coli has significantly increased. In addition, the emergence and worldwide spread of antibiotic-resistant strains has become the most important problem for mankind. Therefore, the search for new alternative drugs is inevitable, timely and unavoidable.
Bacteriophages - bacterial viruses are the most optimal and harmless means against infectious processes caused by microorganisms. Besides, phage therapy has many advantages compared to antibiotics. For example, the effectiveness against antibiotric resistant pathogens, strict specificity to target bacteria, so that they do not to damage the normal microflora, etc.
Along with the therapeutic use of bacteriophages, they are widely used as for bio-sanitary purposes. For example, they are used for the decontamination of meat and seafood, raw fruitvegetable and other foods, as well as for disinfection of the surfaces, which are in contact with contaminated food.
After the FDA approval the first phage-based product (ListShield) on August 18, 2006, the interest towards development of new bacteriophages preparations which insure food safety has gradually increased. Consequently, the research has been actively ongoing which is aiming isolation of the new phages and their uses for different purposes, such as therapeutic, biocontrolling and decontaminating means.