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ღრძილის რეცესიის აღდგენა ძვლის ტვინის ღეროვანი უჯრედებისა და ადამიანის ამნიონისაგან მიღებული დეცელულარიზირებული მემბრანის გამოყენებით
Date Issued
2020
Author(s)
Advisor(s)
Institution
Faculty
Abstract
About 50% to 90% of the world population is affected by the gingival
recession. Currently, it is one of the most important challenges of the dentistry since the
marginal edge of the gum shifts to the mucogingival junctionwhich exposes the tooth
root. The treatment methods include various conservative and surgical methods.
Conservative treatment does not fully meet the clinician’s requirements, and the most
commonly used surgical methods are when they transplant free tissue flaps or the ones
with a vascular pedicle. Despite the positive results, the above mentioned methods of
treatment have disadvantages: additional donor site, and in the cases of generalized
gingival recession, an insufficient amount of tissues required for transplantation. At the
same time, the risk of complications and postoperative pain increases considerably.
Because of these negative effects, a constant development of new and more refined
methods of treatment takes place.
The objective of this study is to develop a new biologically active membrane, created by
the composite of decellularized human amniotic membrane and bone marrow stem cells,
for the treatment of gingival recession.
recession. Currently, it is one of the most important challenges of the dentistry since the
marginal edge of the gum shifts to the mucogingival junctionwhich exposes the tooth
root. The treatment methods include various conservative and surgical methods.
Conservative treatment does not fully meet the clinician’s requirements, and the most
commonly used surgical methods are when they transplant free tissue flaps or the ones
with a vascular pedicle. Despite the positive results, the above mentioned methods of
treatment have disadvantages: additional donor site, and in the cases of generalized
gingival recession, an insufficient amount of tissues required for transplantation. At the
same time, the risk of complications and postoperative pain increases considerably.
Because of these negative effects, a constant development of new and more refined
methods of treatment takes place.
The objective of this study is to develop a new biologically active membrane, created by
the composite of decellularized human amniotic membrane and bone marrow stem cells,
for the treatment of gingival recession.
Degree Name
Ph.D in Medicine
Degree Discipline
კლინიკური და ტრანსლიაციური მედიცინა
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Sadoktoro Karalashvili.pdf
Description
ღრძილის რეცესიის აღდგენა ძვლის ტვინის ღეროვანი უჯრედებისა და ადამიანის ამნიონისაგან მიღებული დეცელულარიზირებული მემბრანის გამოყენებით
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3.23 MB
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Adobe PDF
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(MD5):ad4d0134f1f4a2e4bf83388809fe2ccc