2,2’-(ნაფთილენ-1,5-დი-ილ-ბის(აზანედილ))ბის(თიაზოლ-4(5H)-ონის) სინთეზი და კვლევა.

At present, the synthesis of biologically active materials is a urgent problem. It is especially important to create preparations whose activity helps diminish, slow down or entirely stop spreading of cancerous cells. In this respect, some compounds containing imidazole and thiazole rings are notable, which revealed intercalation and inhibitory activity.
On the other hand, naphthalene ring-containing esters show antimicrobial, antiinflammatory, analgesic and antihypoxial properties. It is noteworthy that naphthalene derivatives synthesized earlier at the Department of Organic Chemistry of Ivane Javakhishvili Tbilisi State University also revealed antimicrobial properties.
We condensed the naphthalene ring-containing heterocyclic systems synthesized earlier at the department of organic chemistry in order to synthesize new possible biologically active heterocyclic compounds and their derivatives with imidazole and thiazole rings. In particular, we synthesized and studied the compounds containing novel thiazole and imidazole rings on the 1,3-diaminonaphthalene basis. We worked out obtaining methods, determined the structure of intermediate and final products, and optimized the reaction conditions.