Lomaia, MariamMariamLomaiaTsiklauri, Sh.Sh.TsiklauriKhechinashvili, T.T.KhechinashviliTsabadze, M.M.TsabadzeNakudashvili, N.N.Nakudashviliლომაია, მარიამმარიამლომაია2025-03-052025-03-052022https://openscience.ge/handle/1/8043In this work, we discuss the development of a new method of immunogenesis and treatment of infectious and infectious-allergic chronic sinusitis and its effectivness, based on new targeted methods of immunocorrection, taking into account the severity of the inflfl ammatory process, current complaints and duration. 52 patients were under observation. The results of treatment with an aerosol of recombinant interferon αа-2Ь (in the form of Gripferon drops) in different types of chronic rhinosinusitis were studied. It has been shown that aerosol therapy with Gripferon gives promising results – subjective condition of patients and rhinoscopic and endoscopic data, as well as improvement of nasal olfactory function and regulation of mucociliary clearance, which indicates the effectiveness of this method of treatment.enrhinosinusitisgripferonaerosol therapyneutrophilseosinophilsრინოსინუსიტიგრიპფერონიაეროზოლური თერაპიანეიტროფილებიეოზინოფილებიtext::journal::journal article10.51231/2667-9507-2022-001-04-11-17